Navigating the gloomy sewers in the Resident Evil 2 remake can be a daunting experience due to limited supplies and terrifying bio-weapons. Among the various locked containers hidden across this subterranean area, the safe in the Treatment Pool Room offers valuable character upgrades that significantly improve your combat capabilities. Knowing how to reach this area and dial the correct combination ensures you do not waste precious resources searching in dangerous corridors.

Locating the Treatment Pool Room in the Sewers

The Treatment Pool Room is situated within the middle section of the Sewers, acting as a key landmark during the mid-game story progression. Players usually arrive here after navigating past the Monitor Room and crossing the main walkway bridge. The room connects several crucial paths, making it a place you will visit multiple times during your escape.

Upon entering the room, you will notice a large platform bridge that can be lowered using a nearby wall lever. A zombie rests near the right side of the platform right next to the safe itself, so clear the threat before interacting with the lock. Take time to scout the surrounding tables and walkways for extra supplies like herbs before moving forward.

Finding the Safe and the Combination Code

Unlike many other safes throughout the game that require searching for hidden files in distant rooms, this particular lock solution is surprisingly straightforward. The developer left the combination written directly on the side of the safe container in white chalk. This subtle detail allows observant players to crack the code immediately without backtracking to other areas.

Even though the clue is right next to the mechanism, many players miss it due to the dark environment and distracting threats. Paying close attention to environmental textures is essential when exploring the dangerous sewers. Checking the side wall of the safe reveals the exact numbers needed to turn the dial successfully.

Unlocking the Safe Step-by-Step Dial Solution

To open the Treatment Pool Room safe, approach the dial interface and prepare to turn the lock in the correct directional sequence. First, turn the dial counterclockwise to the left until it reaches number 2. Next, rotate the dial clockwise to the right to hit number 12, and finish by turning counterclockwise to the left to number 8.

Once you input Left 2, Right 12, Left 8, press the open prompt to unlatch the heavy door. If you make a mistake while turning the dial, simply reset the sequence and start over from the first direction. Unlocking it quickly lets you grab your reward and proceed without lingering near potential sewer threats.

Rewards for Leon and Claire Scenarios

The contents inside the safe vary depending on whether you are playing as Leon S. Kennedy or Claire Redfield. Playing as Leon grants you the Shotgun Stock (W-870), an attachment that drastically reduces weapon recoil and speeds up shooting rates. This upgrade turns your standard shotgun into a far more reliable weapon for taking down tough enemies.

If you are exploring the Sewers as Claire, opening the safe yields the Reinforced Frame for her SLS 60 handgun. Equipping this modification allows Claire to load high-powered rounds capable of dealing immense damage to boss-level targets. Claiming these upgrades early in your Sewer exploration provides a major advantage for the brutal fights ahead.